Customize your lead discovery solutions
BioBlocks has served clients as a complete chemistry department, as an additional resource to enhance an internal team or as a fully integrated partner in a drug discovery team. Utilizing an integrated approach, we have delivered promising lead compounds in broad therapeutic and target class areas, including kinases, GPCRs, ion channels, phosphatases, and proteases. We realize that each target class has unique challenges, and have the experience to help you successfully navigate them.
In all cases, you will find it easy and affordable to collaborate with us.
How we have served our clients
- Served as the chemistry department for a virtual biotech
- Patents issued in congested IP space
- Program sold to Pharma
- Served as a customized chemistry department for a small biotech
- Difficult target and assay
- Leads substantially improved over hits despite long SAR cycles
- Program sold to Pharma
- Served as a complementary chemistry team for a medium sized biotech
- Pharmaceutical properties improvement allowed in vivo activity
- Program met external milestone
We are proud to have a track record of delivering exceptional service to our clients. In 2014, BioBlocks became a designated “select partner” for the specialized outsourcing needs of one of the top global pharmaceutical companies. Nothing makes us happier than a highly satisfied client.
What our clients are saying
"Our lead discovery and optimization collaboration with BioBlocks has helped us reach important milestones in our first project with them, leading to increased momentum and visibility for the initiative. We have found BioBlocks’ results- oriented medicinal chemistry approach to be a very valuable asset to our drug discovery programs, and we are pleased to continue our collaboration with them."
– Qingping Zeng, Associate Director, Medicinal Chemistry and Lead Discovery of MannKind Corporation
How we could work together
To advance your drug discovery program, choose our standard medicinal chemistry service or include the additional advantages of our Leap-to-Lead™ platform.
|BioBlocks Collaboration Deliverables||Standard Medchem||L2L Extended Medchem|
|Dedicated FTEs at our Hungarian site||✓||✓|
|Open access to chemists at our San Diego site||✓||✓|
|Medicinal chemistry review of your project||✓||✓|
|High quality solutions to difficult problems||✓||✓|
|Co-created IP is yours||✓||✓|
|Flexible project planning with unlimited changes||✓||✓|
|Worldwide reagent access||✓||✓|
|Analytical data for every compound||✓||✓|
|Documentation to match your requirements||✓||✓|
|Timely progress reports||✓||✓|
|Patent ready procedures||✓||✓|
|Interactive SAR discussions||✓||✓|
|Regular project discussions||✓||✓|
|Project plans tailored to your goals||✓||✓|
|Access to CFL (BioBlocks proprietary 3D fragment library) for FBLD screening||✓|
|Access to FBLD assays via BioBlocks collaborators||✓|
|Improve patent coverage for your current series using the Syntheverse™||✓|
|Realistic scaffold hopping using the Syntheverse™||✓|